COM.on C.A.4:e2/5-13     Online published on Feb.6, 2010.
doi:10.4236/coca.2010.41002
REPORT
 Similarities in Patrilineal Genetics between the Han Chinese of Central China and Chaoshanese in Southern China

ZHANG Fenghuan 1, LI Hui 2, HUANG Liqun 3, LU Yan 2, HU Shengping 1,4

1. Molecular Biology Laboratory, Shantou University Medical College, Shantou GD515031, China; 2. MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai 200433, China; 3. Clinical Laboratory, First Affiliated Hospital, Shantou University Medical College, Shantou GD515041, China; 4. Forensic Genetics Laboratory, Shantou University Forensic Medical Service Center, Shantou GD515031, China

ABSTRACT: Y-chromosome short tandem repeat (Y-STR) loci are widely used to trace the origin of the human populations. In a previous study, we used STR analysis to determine that the Chaoshanese of eastern Guangdong (often regarded as a "typical" southern Chinese population) are a mix between the Han Chinese of central China and indigenous ethnic groups of southern China. To further investigate the Y chromosome of the Chaoshanese and the group's genetic affinity with other Chinese populations, we analyzed six specific Y-STR loci in samples taken from 6,292 individuals from 51 populations, including the Chaoshanese, the Minnamese, and various other East Asian populations. The admixture analysis showed that over 85% of the Chaoshanese Y chromosomes is derived from the Han in central China (MRH: 0.86; MBE: 1.19 ± 0.21) while a very small portion is derived from southern indigenous populations. These findings not only confirm that the Chaoshanese originated from central China, but also reveal that the patrilineal genetics of the Chaoshanese can be mainly attributed to Han males from central China. The principal component and phylogenetic analyses show that the Chaoshanese generally clustered with Han populations from southern China, specifically the Minnamese, Taiwanese, Malaysian Chinese, and Singaporean Chinese populations. The phylogenetic tree and the analysis of molecular variance (AMOVA) showed that Chinese populations tended to cluster based on their linguistic families rather than their geographic distribution, suggesting a strong association between the Y-chromosome and linguistic affiliations. These analyses also revealed that the patrilineal boundary between southern and northern populations was not pronounced.

Key words: Han in Central China; Chaoshanese (Teochew and Swatow); Paternal genetic affinity; Southern indigenous population; Y-chromosomal short tandem repeat (Y-STR)

Recieved: Jan.28, 2010   Accepted: Feb. 5, 2010  Corresponding: sphu@stu.edu.cn

《现代人类学通讯》第四卷e2篇 第5-13页  2010年2月6日网上发行

研究报告

中原汉族是潮汕汉族父系遗传成分的主要贡献者

张凤环1，李辉2，黄立群3，陆艳2，胡盛平1,4

1 汕头大学医学院分子生物学实验室，广东 汕头 515031；2 复旦大学生命科学学院现代人类学教育部重点实验室，上海 200433；3 汕头大学医学院第一附属医院临床实验室，广东 汕头 515041；4 汕头大学司法鉴定中心DNA物证研究室，广东 汕头 515031

摘要： Y染色体短串联重复序列(Y-STR)位点现已普遍用于追溯人类群体遗传起源的研究。居于广东省东部的潮汕汉族是典型中国南方人群，本课题组前期通过分析常染色体STR数据证明了潮汕汉族是中原汉族和南方土著居民融合而成的混合人群。为了进一步研究潮汕汉族的父系遗传结构及与其他中国人群的遗传关系，我们共搜集了含有6个Y-STR位点数据的51个中国人群6292例个体，其中包括课题组前期研究的潮汕和闽南汉族人群，及来自其他研究的南北方汉族、藏缅语族、阿尔泰语系、苗瑶语系、南亚语系和侗台语系人群。融合分析结果显示潮汕汉族中85%以上的父系遗传成分源于中原汉族(MRH: 0.86; MBE: 1.19±0.21), 而来自南方土著的微乎其微, 再次证明了潮汕汉族的中原起源，并进一步提示，中原汉族男性是潮汕汉族父系遗传成分的主要贡献者；主成分分析和聚类分析结果显示潮汕汉族大体上与南方汉族聚类，但在南方汉中更接近闽南、台湾、马来西亚和新加坡汉族人群；遗传树和分子方差分析(AMOVA)结果显示中国人群倾向于按照其语系分组聚类，而非按照其地理分布，显示父系遗传与语言的紧密关联。这些分析显示父系遗传方面，南方和北方人群的界线并不明显。

关键词： 中原汉族；潮汕汉族；父系遗传关系；南方土著；Y染色体短串联重复序列

收稿日期：2010年1月28日  修回日期：2010年2月5日 联系人：胡盛平 sphu@stu.edu.cn

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致谢

本项目得到以下基金支持：香港李嘉诚基金会剑桥大学国际合作项目基金；英国剑桥大学基金；广东省自然科学基金(000819)；汕头大学研究与发展基金(L00007)；汕头市重点科技计划项目(汕府科[2005]116号)。

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