ZHOU Weichen
MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai 200433 China
ABSTRACT: The factors of genes and environment are common causes of diseases. With theories of population genetics, we analyzed the possible causes of diseases on the aspects of population resources, familial inheritance, environment, interactions between genes and environment, physiological, biochemical, and cellular level disorders, respectively. The analyses may provide theoretical basis for genetic consulting, disease study, and health evaluation.
Key words: Population genetics; Disease genes; Environmental factors; Interaction of genes and environment; Susceptibility
Recieved: Nov.23, 2010 Accepted: Dec.8, 2010 Corresponding: arthurzhou10@gmail.com
《现代人类学通讯》第四卷e21篇 第129-133页 2010年12月9日网上发行
专题综述
群体遗传学角度分析疾病病因中的基因和环境因素
周玮晨
复旦大学现代人类学教育部重点实验室,上海200433
摘要:导致疾病的原因主要是基因因素和环境因素。本文运用群体遗传学知识,分别从人群群体角度、家族遗传角度、环境角度、基因与环境交互作用、生理生化及细胞等层面讨论疾病的发病原因,作出相应的分析解释。根据此分析对遗传咨询、疾病研究、健康诊断等提供理论基础。
关键词:群体遗传学;致病基因;环境因素;基因与环境互作;易感性
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